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| − | '''''Back to'''''
| + | #REDIRECT [[CDS]] |
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| − | [[:CDS|CDS]] | + | |
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| − | [[:CDS#Medication-Based_Safety_Rules|Medication-Based Safety Rules]]
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| − | ----
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| − | ==References==
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| − | KAISER PERMANENTE:SAFETY IN PRESCRIBING (SIP). Recommendations for dosing and drug alternatives. Dosing Recommendation in renal dysfunction. FEBRUARY 10, 2003 UPDATE.
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| − | ----
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| − | <table style="background-color: FFFFFF;" border="12">
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| − | ==<th>Examples of Medications Requiring Dosage Adjustments in Renal Insufficiency</th>== <tr>
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| − | <table style="background-color: FFFFFF;" border="4">
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| − | <th align=left>Drug</th><th align=left>GFR</th><th align=left>Dosing recommendation in alert</th><th align=left>Potential safety problem listed in alert</th>
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| − | <tr><td align=left>'''Allopurinol'''</td>
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| − | <td>51-60
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| − | 10-50
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| − | <10
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| − | </td>
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| − | <td>200mg per day maximum
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| − | 150mg per day maximum
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| − | Do not use
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| − | </td>
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| − | <td align=left> Liver and hematoligic toxicity.
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| − | <tr><td align=left>'''Co-trimoxazole'''</td>
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| − | <td>15-30
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| − | <15
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| − | </td>
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| − | <td> 80/400mg twice per day maximum
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| − | Do not use
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| − | </td>
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| − | <td align=left> Crystalluria and kidney stone formation.
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| − | <tr><td align=left>'''Metformin'''</td>
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| − | <td><10
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| − | </td>
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| − | <td>Do not use
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| − | </td>
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| − | <td align=left> Lactic acidosis.
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