The effect of computerized physician order entry on medication prescription errors and clinical outcome in pediatric and intensive care
The intensive care unit environment may require more demanding and complex interventions, as their patients are more critically ill. The process of prescribing medications for these patients may be a complex task. The purpose of the study is to evaluate the effects of Computerized order entry (CPOE)) systems on medication prescription errors, Adverse drug event (ADE) and mortality in intensive care units. 
A literature review was conducted up to the year 2007 on Pubmed, the Cochrane library, and embase.
Twelve observational studies were included in this systematic review. The results showed a decreased risk of medication prescription errors with the use of CPOE. There was no signification reduction in ADE or mortality rates.
In conclusion, CPOE reduces medication prescription error rates. Mortality did not seem to be affected by the use of CPOE. The actual clinical benefits from the application of CPOE systems in ICUs have yet to be determined.
Overall, the study does demonstrate a reduction in medical prescription errors. The implementation process of CPOE could determine the successes and failures at an institution.
- Van Rosse, 2009. The effect of computerized physician order entry on medication prescription errors and clinical outcome in pediatric and intensive care: a systematic review. http://www-ncbi-nlm-nih-gov.ezproxyhost.library.tmc.edu/pubmed/19336379